Abstract
The effect of long administration of rocket (J) alternatively with cyclophosphamide (Cp) on some cytogenetic parameters in white mice bone marrow cells was studied , these inlcluded mitotic index (MI) , micronuclei (Mn) formation , and chromosomal aberrations (Ch. ab.) . In addition the effect was studied on germ cell (Sperms) by scoring the number of sperm-head abnormalities and type of abnormalities . Results indicated that Cp reduced the MI by 55 % of the normal value (6.84) , while treatment of rocket with the drug (J+Cp) restored 85.5 % (5.85) of the normal value , followed by (Cp/J) restored 83.3 % (5.7) and the treatment (J/Cp) restored the lowest level 71.5 % (4.89) . Cp raised the Mn to 18.16 which is (17) times the natural value , administration of rocket with the drug simultaneously reduced the number to 6.02 , the best treatment was (Cp/J) as the number lowered to (5.860 , then the treatment J/Cp (6.76) , all of them were higher than the negative control with significant difference (P
