Abstract
This study was carried out to evaluate the effects of boiled extract of oak (Quercus aegilops) leaves on blood, glucose, cholesterol, triglyceride (TG), High density Lipoprotein-cholesterol (HDL-C). Low density lipoprotein – cholesterol (LDL-C) and risk ratio in male rabbits, also to study the effect of treatment on the chemical composition of liver and thigh as well as the glycogen level . Rabbits (5-6 months old) were divided into two groups (6 rabbits each). Rabbits in the 1st group was treated daily for 28 days with oak leaves boiled extract (250 mg/kg. B. wt) orally. The 2nd group treated with distilled water, served as control. Treatment caused a significant decrease in blood glucose, cholesterol, and LDL-C as compared with control values , risk factor also reduced significantly as compared with control , TG increased significantly as compared with control , treatment also causes a significant increase in liver and thigh glycogen concentrations as compared with control group , also a significant increase in dry matter % , ether extract % , crude protein % and ash % , and a significant decrease in carbohydrate % in both liver and thigh as compared with the control group . In a separate experiment, the single dose of oak leaves boiled extract caused a significant decrease in blood glucose level at 3, 12 and 24 hrs after drenching as compared with pre drenching level . Results revealed that oak leaves boiled extract caused an improvement in lipid profile, and hypoglycemic effect continue significantly for 24 hrs.
