Abstract
Different concentrations of cold aqueous extract Ficus carcia leaves were studied on the levels of glucose, cholesterol, triglycerides, total lipids, Aspartate amino transferase (AST) and Alanine amino transferase (ALT) activity and total protein in the serum and in the liver glycogen level and total protein in the liver and heart of the normal rats. 25 male albino wistar rats derived were used, with age 3-4 month, and weight 225-300 g. The rats were divided randomly into five groups. The first group was injected with distilled water and consumed the control group. The second, third, fourth and fifth groups were injected intraperitonealy with 100, 200, 300, and 400 mg/kg B.W with aqueous extract of Ficus carcia leaves. The blood, liver, and heart tissues were collected. The statistical results showed a significant decrease in the glucose, cholesterol, triglycerides and total lipids. While a significant increase in the Aspartate amino transferase (AST) and Alanine amino transferase (ALT) activity was showed in group 5of both compared with the control group (P < 0.05). In the tissues a significant reduction showed in the liver glycogen, for all concentration of the injected extract while insignificant differences were showed in the liver and heart total protein compared with the control group (P < 0.05). It was concluded that the cold aqueous extract of ficus carcia leaves has a biochemical role in the regulation and controlling the metabolic reaction through decreasing the glucose and lipids levels.
