Abstract
The effect of rocket ( Eruca sativa ) leave juice on induction of sperm - head abnormalities was studied using the white mice males , the effect of cyclophsphamide (Cp) on such abnormalities was studied as well . In addition to studying the effect of different combinations between the plant juice and the mutagen (Cp) . The results indicated that rocket juice 0.1 , 0.25 , 0.5ml / animal administrated orally had no effect on induction of sperm - head abnormalities , while Cp induced abnormalities in order of 5 times the background level , which remain unrepaired even after 6 days . The combinations such as using the juice before the mutagen (J/Cp) or using the juice with the mutagen (J+Cp) were able to lower the abnormalities almost to the baseline level (i.e., the negative control) or slightly higher but , without statistical significancy (P<0.01) . Treatment of animals with juice after mutagen (Cp/J) was able to restore the normality in manner depending on time and reaching the normal starting baseline after 6 days. Types of abnormalities were different and Cp induced sperms without hooks at high level , which also represented the highest abnormalities when animals treated with mutagen and juice simultaneously . The J/Cp treatment was able to reduce all types of abnormalities compared to the positive control and was statically significant (P<0.01) and some abnormalities were disappeared such as the rod – head shaped sperm . (Cp/J) treatment resulted in persistence of some abnormalities even after 6 days .